The part number 20G1F3C540KNDNNNNN-P50 appears to be related to a research project funded by the National Institutes of Health (NIH) under the P50 Specialized Center grant mechanism. The project is focused on understanding the interactions between peripheral inflammation and neurocognitive systems in the development of addictive behaviors, particularly among African Americans.
The project, titled "Center for Translational and Prevention Science," is a collaborative effort between researchers from various disciplines, aiming to investigate the biological and neurocognitive contributors to addictive behaviors and the potential of family-centered prevention programming to mitigate the effects of growing up in chronically stressful contexts. The project is led by Principal Investigator Steven Beach and is funded by the National Institute on Drug Abuse (NIDA) from 2020 to 2025.
The project involves three research projects (RPs) that are integrated around the neuroimmune network (NIN) model, which specifies stress-induced alterations in the transactions between peripheral inflammation and neurocognitive systems that subserve emotion regulation in the development of addictive behavior vulnerability. The RPs are:
- RP1 (HARP Transitions): This project assesses neural activity and inflammation in African American emerging adults, ages 18-20, over a two-wave study spanning 2.5 years. It includes bioimaging of NIN-related neural systems, assay of peripheral inflammation, and measures of stress exposure and addictive behaviors.
- RP2 (HARP Foundations): This project conducts a longitudinal, two-year experimental trial with African American youth at age 11 and their primary caregivers. It includes baseline and follow-up assessments with fMRI, inflammatory, and behavioral data to examine the underlying biological mechanisms for the multi-level benefits of family-centered prevention programming.
- RP3 (HARP Generations): This project tests hypotheses about the ways in which the resources and risks that grandparents and parents experience carry forward to shape the development of addictive behavior vulnerabilities and cardiometabolic risks in future generations. It collects data on parent-child relationships, inflammation, and behavior and emotion regulation indicators suggested by the NIN model.
The project's technical specifications, alarm/error codes, user manuals, troubleshooting, programming, and installation details are not directly applicable to this research project, as it is focused on scientific research rather than technical implementation.
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